Cosmetic Procedures: Wrinkles
We've all heard the clicheLs: Wrinkles are a roadmap of your life. But many
of us would rather not be reminded of the distance we've traveled. What can
you do? First, understand what causes wrinkles. Then, if you still want to
reduce wrinkles, explore your treatment options.
What Causes Wrinkles?
The following factors are the most significant:
Aging
Wrinkles are a by-product of the aging process. With age, skin cells divide
more slowly, and the inner layer, called the dermis, begins to thin. The network
of elastin (the protein which causes skin to stretch) and collagen fibers (the
major structural proteins in the skin), which support the outer layer, loosen
and unravel, causing depressions on the surface. With aging, skin also loses
its elasticity, is less able to retain moisture, oil-secreting glands are less
efficient and the skin is slower to heal. All of these contribute to the development
of wrinkles.
Facial Muscle Contractions
Lines between the eyebrows (frown lines) and lines jutting from the corner
of the eyes (crows feet) are believed to develop because of small muscle contractions.
Smiling, frowning, squinting and other habitual facial expressions cause these
wrinkles to become more prominent. Over time, the expressions coupled with
gravity contribute to the formation of jowls and drooping eyelids.
Sun Damage
Exposure to ultraviolet radiation (too much sun) can result in premature aging
of skin. Premature aging of the skin is called photoaging. The ultraviolet
sunrays that cause photoaging damage collagen fibers and cause the excessive
production of abnormal elastin. When ultraviolet light damages skin tissue,
an enzyme called metalloproteinase is produced. This enzyme creates and reforms
collagen. During the process, however, some healthy collagen fibers are damaged,
resulting in a disorganized formation of fibers called solar scars. Wrinkles
develop when the rebuilding process occurs over and over.
Smoking
Healthy skin perpetually regenerates. While old collagen is broken down and
removed new collagen is produced. Researchers have found that smoke causes
a marked reduction in the production of new collagen. A lack of new collagen
results in the development of wrinkles.
What Are the Treatment Options for Wrinkles?
There are numerous over-the-counter treatment options for wrinkles, including
various creams and lotions. Prescription treatments, including the retinoid
cream renova, are also an option.
Removing skin layers to reduce wrinkles or irregular depressions is an effective
way to regain smoother, more youthful looking skin. Dermabrasion (scraping
layers away) and chemical peels (dissolving skin away) are two of the traditional
methods used in skin resurfacing. Laser skin resurfacing with an ablative laser
(such as an erbium or carbon dioxide laser) is another technique that, like
dermabrasion and deeper chemical peels, may require some downtime during the
healing process.
Other lasers, known as non-ablative lasers, may also be beneficial in treating
wrinkles. These lasers work by heating the dermis and stimulating collagen
growth. This process, which leaves the outer layers of skin intact, has no
downtime associated with it. However, the results are not as dramatic as the
ablative lasers which actually remove the surface layers of skin.
Botox collagen and other injections are the addional techniques available to
help minimize wrinkles.
If you are considering treatment for your wrinkles, ask your doctor which
procedure is right for you. There is no replacement for your doctor's professional
advice. Each person has his or her own individual needs; similarly, each procedure
fulfills its own specific need.
For more information, see:
Learn what ingredients
in skin care products may be best for you.
Want to learn how to better take care of your aging skin? Read
this .
Reviewed by the doctors at The Cleveland Clinic, Department of Dermatology.
Edited by by
Cynthia Haines, MD, April 2005, WebMD.
Portions of this page The
Cleveland Clinic 2000-2003
Copyright 2003 content, The Cleveland Clinic
Cosmetic Procedures: Sun Exposure and Skin Cancer
Many people love the warm sun. The sun's rays make us feel good, and in the
short term, make us look good. But our love affair isn't a two way street:
Exposure to sun causes most of the wrinkles and age spots on our faces. Consider
this: One woman at age 40 who has protected her skin from the sun actually
has the skin of a 30-year-old!
We often associate a glowing complexion with good health, but skin color obtained
from being in the sun | or in a tanning booth | actually accelerates the effects
of aging and increases your risk for developing skin cancer.
Sun exposure causes most of the skin changes that we think of as a normal
part of aging. Over time, the sun's ultraviolet (UV) light damages the fibers
in the skin called elastin. When these fibers breakdown, the skin begins to
sag, stretch, and lose its ability to go back into place after stretching.
The skin also bruises and tears more easily -- taking longer to heal. So while
sun damage to the skin may not be apparent when you're young, it will definitely
show later in life.
How Does the Sun Change My Skin?
Exposure to the sun causes:
- Pre-cancerous (actinic keratosis) and cancerous (basal cell carcinoma,
squamous cell carcinoma and melanoma) skin lesions - caused by loss of the
skin's immune function
- Benign tumors
- Fine and coarse wrinkles
- Freckles
- Discolored areas of the skin, called mottled pigmentation;
- Sallowness -- a yellow discoloration of the skin;
- Telangiectasias -- the dilation of small blood vessels under the skin;
- Elastosis -- the destruction of the elastic tissue causing lines and wrinkles.
What Causes Skin Cancer?
Skin cancer is the most prevalent form of all cancers in the U.S. and the
number of cases continues to rise. It is the uncontrolled growth of abnormal
skin cells. This rapid growth results in tumors, which are either benign (noncancerous)
or malignant (cancerous).
There are three main types of skin cancer: basal cell carcinoma, squamous
cell carcinoma and melanoma. Basal cell and squamous cell cancers are less
serious types and make up 95% of all skin cancers. Also referred to as non-melanoma
skin cancers, they are highly curable when treated early. Melanoma, made up
of abnormal skin pigment cells called melanocytes, is the most serious form
of skin cancer and causes 75% of all skin cancer deaths. Left untreated, it
can spread to other organs and is difficult to control.
Ultraviolet (UV) radiation from the sun is the number one cause of skin cancer,
but UV light from tanning beds is just as harmful. Exposure to sunlight during
the winter months puts you at the same risk as exposure during the summertime.
Cumulative sun exposure causes mainly basal cell and squamous cell skin cancer,
while episodes of severe sunburns, usually before age 18, can cause melanoma
later in life. Other less common causes are repeated X-ray exposure and occupational
exposure to certain chemicals.
Who Is at Risk for Skin Cancer?
Although anyone can get skin cancer, the risk is greatest for people who have
fair or freckled skin that burns easily, light eyes and blond or red hair.
Darker skinned individuals are also susceptible to all types of skin cancer,
although their risk is substantially lower.
Aside from complexion, other risk factors include having a family history
or personal history of skin cancer, having an outdoor job and living in a sunny
climate. A history of severe sunburns and an abundance of large and irregularly-shaped
moles are risk factors unique to melanoma.
What Are the Symptoms of Skin Cancer?
The most common warning sign of skin cancer is a change on the skin, typically
a new mole or skin lesion or a change in an existing mole.
- Basal cell carcinoma may appear as a small, smooth, pearly or waxy bump
on the face ears and neck; or as a flat, pink/red- or brown- colored lesion
on the trunk or arms and legs.
- Squamous cell carcinoma can appear as a firm, red nodule, or as a rough,
scaly flat lesion that may itch, bleed and become crusty. Both basal cell
and squamous cell cancers mainly occur on areas of the skin frequently exposed
to the sun, but can occur anywhere.
- Melanoma usually appears as a pigmented patch or bump. It may resemble
a normal mole, but usually has a more irregular appearance.
When looking for melanoma, think of the ABCD rule that tells you the signs
to watch for:
- Asymmetry - the shape of one half doesn't match the other
- Border - edges are ragged or blurred
- Color - uneven shades of brown, black, tan, red, white or blue
- Diameter - A significant change in size (greater than 6mm)
How is Skin Cancer Diagnosed?
Skin cancer is diagnosed only by performing a biopsy. This involves taking
a sample of the tissue, which is then placed under a microscope and examined
by a dermatopathologist, or doctor who specializes in examining skin cells.
Sometimes a biopsy can remove all of the cancer tissue and no further treatment
is needed.
How is Skin Cancer Treated?
Treatment of skin cancer is individualized and is determined by the type of
skin cancer, its size and location and the patient's preference.
Standard treatments for non-melanoma skin cancer (basal cell or squamous cell
carcinomas) include:
- Mohs surgery (for high-risk non-melanoma skin cancers) | excision of cancer
and some extra tissue
- Electrodesiccation and curettage | physically scraping away the skin cancer
cells followed by electrosurgery
- Cryosurgery or freezing
- Laser therapy
- Drugs (chemotherapy, retinoids)
Standard treatments for melanoma skin cancer include:
- Wide surgical excision
- Sentinel lymph node mapping (for deeper lesions) | to determine if the
melanoma has spread to local lymph nodes
- Drugs (chemotherapy, biological response modifiers)
- Radiation therapy
- New methods in clinical trials are sometimes used to treat skin cancer.
How Can I Help Prevent Skin Cancer?
Nothing can completely undo sun damage, although the skin can sometimes repair
itself. So, it's never too late to begin protecting yourself from the sun.
Your skin does change with age -- for example, you sweat less and your skin
can take longer to heal, but you can delay these changes by staying out of
the sun. Follow these tips to help prevent skin cancer:
- Apply sunscreen with a sun protection factor (SPF) of 15 or greater 30
minutes before sun exposure and then every few hours thereafter.
- Select cosmetic products and contact lenses that offer UV protection.
- Wear sunglasses with total UV protection.
- Avoid direct sun exposure as much as possible during peak UV radiation
hours between 10:00 a.m. and 3:00 p.m.
- Perform skin self-exams regularly to become familiar with existing growths
and to notice any changes or new growths.
- Eighty percent of a person's lifetime sun exposure is acquired before age
18. As a parent, be a good role model and foster skin cancer prevention habits
in your child.
Learn how to protect
your skin .
Read about the
effects of aging on skin .
Reviewed by the doctors at The Cleveland Clinic Department of Dermatology.
Edited by by
Cynthia Haines, MD, April 2005, WebMD.
Portions of this page The
Cleveland Clinic 2000-2003
Copyright 2003 content, The Cleveland Clinic.